University/Organization
Department of Biology
Howard University
Washington, DC
Title
Identifying Potential Roles for Sin3a as a Metastasis Suppressor in E1B55k-deleted Ad Infected Cells
Synopsis:
The main goal of this project is to identify ways in which the gene Sin3a, a known metastasis suppressor in triple negative breast cancer cell lines, can suppress metastasis in other cell lines treated with E1B55K-deleted virus. We do this as another step into identifying therapies and additional treatment options for patients with metastatic disease, as they currently have limited treatment options available to them.